Multidrug Resistance During Chemical Carcinogenesis: A Mechanism Revealed?
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چکیده
منابع مشابه
Multidrug resistance during chemical carcinogenesis: a mechanism revealed?
The classic Solt-Farber model of chemical carcinogenesis in rat liver (7) involves sequential treatment of rats with diethylnitrosamine, partial hepatectomy, and 2(acetylamino)fluorene (AAF). After several weeks, the rats develop multiple preneoplastic hepatic nodules, and some of these become frank hepatocarcinomas after several months. Cells derived from the nodules appear to be resistant to ...
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ژورنال
عنوان ژورنال: JNCI Journal of the National Cancer Institute
سال: 1988
ISSN: 0027-8874,1460-2105
DOI: 10.1093/jnci/80.17.1352